Apogen GVP is not a drug. It’s a patented nutritional supplement concentrated and purified from proprietary strain FEM-101 and organically grown spirulina, a healthful bluegreen algae so rich in nutrients it’s commonly called a superfood. It takes the equivalent of 450 tablets of spirulina to make one serving of Apogen GVP, or more than 13,000 tablets to make a single box!

Apogen GVP does not kill viruses. Instead, it protects cells by creating a "viral firewall" that many viruses can’t cross. While Apogen GVP is not intended to treat or prevent illness, just like vitamins, minerals and other nutritional supplements, Apogen GVP’s scientifically demonstrated action helps support the body’s natural defenses.

In addition different types of flu virus, Apogen GVP has also been shown to inhibit a number of other pathogens including several potentially serious intestinal viruses (Enterovirus 71 and Coxsackie virus A162) that may cause illness, paralysis and even death, especially in children. Additional research is currently underway to explore Apogen GVP’s range and mechanisms of action.

Apogen® — Safety and Effectiveness

Recently, scientists at National Chang Gung University in Taiwan compared the relative effectiveness of Apogen and the most popular prescription drug for treating type A influenza, including the current H5N1 "bird flu."

Unlike the popular prescription drug, which is a pharmaceutical drug that works to disable an essential part of a type A influenza virus’s structure, Apogen is a food-based, organic nutrient complex that works to protect cells from penetration by the virus.

In this study, the scientists determined the amount of Apogen needed to block 50% of the spread of the virus in a cell culture. The numerical results, called IC50 — short for inhibitory concentration 50% — showed that it took 12.3 times less Apogen to achieve the same virus inhibiting effects as the popular drug.

The study also determined the relative cellular toxicity of Apogen, determining how high a concentration is required to kill 50% of the cells. This factor, called LC50 — short for lethal concentration 50% — was more than 3 times better for Apogen than the popular drug. This means that cells can tolerate much higher amount of Apogen than the popular drug, even though much less is required to be effective.

Putting these two numbers together determines the "safety margin" — a measure of how many times the effective concentration it takes to produce a toxic reaction. Larger numbers are better. In this experiment with a virulent type A influenza, the safety margin for the popular drug was 72, while for Apogen it was more than 2800!

As these results clearly demonstrate, Apogen was 12.3 times more effective at inhibiting the spread of viral plaque than the popular drug and more than 3 times less toxic to the experimental cells, providing a safety margin almost 40 times better.

Live Mice Study

Groups of mice were exposed to 3 different levels of an extremely pathogenic type A influenza virus. Half of the mice in each group were orally administered a small dose of Apogen once per day, starting 6 hours after viral exposure. Researchers tracked body weight and mortality for all groups versus a control population fed Apogen but not exposed to the virus.

Results: All unprotected animals died within 2 to 5 days of viral exposure, at a rate proportional to their viral load. All animals protected with Apogen survived, independent of the their viral load. In other words, while the mice with even the smallest viral load all died from their influenza exposure, all mice protected with Apogen survived – even those exposed to 100 times more virus.

Apogen® GVP

Cell Culture Studies

Cell cultures tests were performed using standard MDCK cells exposed to Enterovirus-71, a potentially lethal intestinal virus. The first photo shows normal, uninfected cells seen through the microscope. The second picture shows the type of cytopathic damage that occurs when virus particles enter cells and replicate. The last picture shows how cells exposed to the same level of virus are protected when Apogen is present. No viral cytopathic damage is observed and cells continue to function normally.

All studies conducted at the School of Medical Technology of National Chang Gung University in Taiwan

1. In an independent scientific study of highly pathogenic influenza virus type A/WSN/H1N1 conducted at School of Medical Technology of Chang Gung University , Taiwan.

2. Shih SR, Tsai KN, Li YS, Chueh CC, Chan EC. “Inhibition of Enterovirus 71-Induced Apoptosis by Allophycocyanin Isolated From a Blue-Green Alga Spirulina platensis,” Journal of Medical Virology. 2003; 70: 119-125.     DOWNLOAD FILE (PDF)